Epilepsy is a severe brain disorder affecting numerous patients.Recently, it is inferred that modulation of microRNA-155 (miR-155) could serve as a promising treatment of mesial temporal lobe epilepsy (MTLE).In the current study, the therapeutic potential of miR-155 antagonist against TLE was evaluated and the underlying mechanism involved in this
Outer Membrane Vesicles from Acinetobacter baumannii: Biogenesis, Functions, and Vaccine Application
This review focuses on Acinetobacter baumannii, a Gram-negative bacterium that causes various infections and whose multidrug resistance has become a significant challenge in clinical practices.There are multiple bacterial mechanisms in A.baumannii that participate in bacterial colonization and immune responses.It is believed that outer membrane ves
Maculopathy after long-term use of fondaparinux, a heparin mimetic and heparanase inhibitor
Purpose: To report maculopathy associated with the long-term use of fondaparinux, a heparin mimetic and inhibitor of the extracellular matrix enzyme, heparanase.Observations: A 41-year-old woman receiving thrice weekly injections of fondaparinux as prophylaxis against deep vein thrombosis for 9 years noticed ribavirin coupon gray spots in her visio